Prof. Kavita Babu
Associate Professor and India Alliance Senior Fellow, Centre for Neuroscience, IISc.
Prof. Kavita Babu’s lab is interested in understanding how neurons “talk” to other neurons and to the muscles that are controlled by neurons. We are interested in understanding the signaling mechanisms underlying neuronal communication through both neuropeptides and cell surface molecules. To study neuronal crosstalk, she employ the small free-living nematode worm called Caenorhabditis elegans or C. elegans for short. Using this organism that has only 302 neurons she can employ molecular, genetic and behavioral methods to study neuropeptidergic signaling between neurons as well as the signaling role of cell adhesion molecules like claudins at the neuromuscular junction.
Some of the ongoing projects in her lab include:
a) Signaling role of cell adhesion molecules at the synapse. For this project she largely focus on how a class of molecules called claudins allow for normal synaptic function.
b) Understanding how neurons communicate with each other using neuropeptides and how these neuropeptide-based circuits allow the free-living nematode Caenorhabditis elegans to modulate locomotion.
c) More recent work involves looking at molecular and development aspects of long-term memory using Caenorhabditis elegans as the model of choice.